의학서적전문 "성보의학서적"의 신간의학도서입니다.

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering the full range of common and rare nonneoplastic renal diseases, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, Diagnostic Pathology: Kidney Diseases, fourth edition, is a visually stunning, one-stop resource for every practicing pathologist, nephrologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource.

Key Features

Provides a comprehensive source for key pathologies and clinical features of more than 265 kidney diseases
Features two dozen new chapters on a variety of timely topics, including COVID-19 nephropathies, xenografts, artificial intelligence (AI), digital pathology analysis, harmonized nephropathology terminology, newly identified types of amyloidosis, common artifacts and pitfalls on kidney biopsy, vaccination-associated renal disease, crystal nephropathies, and much more
Includes updates from the International Kidney and Monoclonal Gammopathy (IKMG) research group, the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for IgG4-related disease, Banff Foundation for Allograft Pathology, and others
Details updated genetic causes of nephrotic syndromes and antinephrin antibodies in podocytopathies—by the investigator who discovered it
Discusses the newly identified variant IgG nephropathy and novel membranous autoantigens
Contains chapters on techniques, including immunofluorescence on paraffin sections, C4d staining, and polyomavirus detection in tissue  
Contains more than 4,300 print and online images, including high-resolution photographs and histologic images, full-color medical illustrations, radiologic images, and more
Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference at the point of care
Shares the expertise of internationally recognized authors who provide fresh perspectives on multiple topics, with a particular emphasis on practical information that directly assists in making and supporting a diagnosis
Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

Author Information

By Robert B. Colvin, MD, Benjamin Castleman Distinguished Professor of Pathology, Department of Pathology, Harvard Medical School, Pathologist-in-Chief, Emeritus, Massachusetts General Hospital, Boston, Massachusetts; Anthony Chang, MD, Professor of Pathology, Director, UChicago Medical Laboratories, Director, Renal Pathology and Renal Pathology Fellowship, Associate Director, Pathology Residency Program, The University of Chicago, Chicago, Illinois and Lynn D. Cornell, MD , Associate Professor of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota

-도서목차-

SECTION 1: INTRODUCTION AND OVERVIEW

4 Introduction to Renal Pathology

Robert B. Colvin, MD

24 Normal Kidney Structure

Neeraja Kambham, MD and Anthony Chang, MD

36 Normal Kidney Development

Sanjay Jain, MD, PhD and Yasar Caliskan, MD

46 Kidney Biopsy Evaluation and Reports

Lynn D. Cornell, MD, Surya V. Seshan, MD, and Anthony

Chang, MD

50 Harmonized Nephropathy Terminology

Mark Haas, MD

54 Common Artifacts and Pitfalls

Lynn D. Cornell, MD

SECTION 2: GLOMERULAR DISEASES

PODOCYTOPATHIES

60 Minimal Change Disease

A. Brad Farris, III, MD and Astrid Weins, MD, PhD

68 Classification of Focal Segmental Glomerulosclerosis

A. Brad Farris, III, MD and Astrid Weins, MD, PhD

72 Etiologic Classification of Focal Segmental

Glomerulosclerosis

Robert B. Colvin, MD

74 Focal Segmental Glomerulosclerosis, Primary

A. Brad Farris, III, MD and Astrid Weins, MD, PhD

82 Focal Segmental Glomerulosclerosis, Adaptive

(Secondary)

A. Brad Farris, III, MD and Astrid Weins, MD, PhD

88 Collapsing Glomerulopathy

A. Brad Farris, III, MD and Astrid Weins, MD, PhD

MEMBRANOUS NEPHROPATHY AND VARIANTS

98 Introduction to Membranous Nephropathy

Robert B. Colvin, MD

108 Etiologies of Membranous

Glomerulonephritis_Table

Robert B. Colvin, MD

110 Introduction to Membranous Nephropathy

Anthony Chang, MD

116 Mebranous Nephropathy Due to PLA2R

Autoantibodies

Anthony Chang, MD and Sanjeev Sethi, MD

120 Membranous Nephropathy Due to non-PLA2R

Antibodies

Anthony Chang, MD and Sanjeev Sethi, MD

124 Membranous Nephropathy Associated With

Systemic Disease

Anthony Chang, MD

128 Membranous Nephropathy With Organized Deposits

Anthony Chang, MD

132 Membranous Nephropathy With Anti-TBM

Antibodies

Robert B. Colvin, MD

134 Podocyte Infolding Glomerulopathy

Shane Meehan, MB, BCh

IGA-RELATED GLOMERULONEPHRITIS

136 Overview of IgA-Related Glomerular Diseases

Shane Meehan, MB, BCh

140 IgA Nephropathy

Lynn D. Cornell, MD, Robert B. Colvin, MD, and Ian Roberts, MBChB, FRCPath

154 IgA Vasculitis (Henoch-Schönlein Purpura)

Anthony Chang, MD and Ian Roberts, MBChB, FRCPath

160 IgA Acute Glomerulonephritis Associated With

Staphylococcus aureus

Robert B. Colvin, MD and Ian Roberts, MBChB, FRCPath

164 Hepatic Disease With IgA Deposition

Robert B. Colvin, MD

SLE AND RELATED AUTOANTIBODYMEDIATED DISEASES

166 Systemic Lupus Erythematosus

Shane Meehan, MB, BCh, Robert B. Colvin, MD, and Ingeborg Bajema, MD

184 Mixed Connective Tissue Disease

A. Brad Farris, III, MD

186 Idiopathic Nonlupus Full-House Nephropathy

Ingeborg Bajema, MD and Emilie Rijnink, MD, PhD

188 Mixed Cryoglobulinemic Glomerulonephritis

A. Brad Farris, III, MD and Charles Alpers, MD

ANTI-GBM DISEASES

194 Anti-GBM Glomerulonephritis

Anthony Chang, MD

202 Atypical Anti-GBM Disease

Lynn D. Cornell, MD

COMPLEMENT-RELATED GLOMERULONEPHRITIS

206 Classification of MPGN and Complement-Related Diseases

Robert B. Colvin, Md
210 Dense Deposit Disease

A. Brad Farris, III, MD

216 C3 Glomerulonephritis

Lynn D. Cornell, MD

222 C1q Nephropathy

Neeraja Kambham, MD

228 C4 Glomerulopathy

Sanjeev Sethi, MD

232 MPGN With Immune Complexes

A. Brad Farris, III, MD, Jean Hou, MD, and Mark Haas, MD

MONOCLONAL IMMUNOGLOBULIN DISEASES OF GLOMERULI

240 Introduction to Diseases With Monoclonal

Immunoglobulin Deposits

Robert B. Colvin, MD

244 Monoclonal Immunoglobulin Deposition Disease

Lynn D. Cornell, MD

252 Proliferative Glomerulonephritis With Monoclonal

IgG Deposits

Lynn D. Cornell, MD

256 Membranous Glomerulonephritis With Masked IgG ?

Deposits

Christopher P. Larsen, MD and Tiffany Caza, MD

260 Type I Cryoglobulinemic Glomerulonephritis

Robert B. Colvin, MD and Evan Farkash, MD, PhD

264 Waldenström Macroglobulinemia

Anthony Chang, MD

266 Crystalglobulin Glomerulonephritis

Anthony Chang, MD and Mariam Priya Alexander, MD

AMYLOIDOSIS

270 Amyloidosis Classification

A. Brad Farris, III, MD and Sanjeev Sethi, MD

276 AL/AH Amyloidosis

A. Brad Farris, III, MD and Sanjeev Sethi, MD

282 AA Amyloidosis

A. Brad Farris, III, MD and Sanjeev Sethi, MD

286 AFib Amyloidosis

A. Brad Farris, III, MD and Sanjeev Sethi, MD

288 AGel Amyloidosis

Sanjeev Sethi, MD

290 ALECT2 Amyloidosis

Christopher P. Larsen, MD, Sanjeev Sethi, MD, and Tiffany Caza, MD

292 AApoAI Amyloidosis

A. Brad Farris, III, MD and Sanjeev Sethi, MD

293 AApoAII Amyloidosis

Robert B. Colvin, MD and Sanjeev Sethi, MD

294 AApoAIV Amyloidosis

Sanjeev Sethi, MD

295 AApoCII Amyloidosis

Sanjeev Sethi, MD

296 ATTR Amyloidosis

A. Brad Farris, III, MD and Sanjeev Sethi, MD

IDIOPATHIC FIBRILLARY GLOMERULOPATHIES

298 Diseases With Organized Deposits

Robert B. Colvin, MD

302 Fibrillary Glomerulopathy

Anthony Chang, MD

308 Immunotactoid Glomerulopathy

Anthony Chang, MD and Charles Alpers, MD

312 Fibronectin Glomerulopathy

Neeraja Kambham, MD

DIABETIC AND RELATED RENAL DISEASE

316 Diabetic Nephropathy

Neeraja Kambham, MD and Ian Roberts, MBChB, FRCPath

326 Metabolic Syndrome/Obesity-Related Glomerular Disease

Shane Meehan, MB, BCh

330 Idiopathic Nodular Glomerulopathy

A. Brad Farris, III, MD and Ian Roberts, MBChB, FRCPath

INFECTION-RELATED GLOMERULAR DISEASE

334 Overview of Infection-Related Glomerular Disease

Shane Meehan, MB, BCh

338 Acute Poststreptococcal Glomerulonephritis

A. Brad Farris, III, MD

346 Postinfectious Glomerulonephritis,

Nonstreptococcal

A. Brad Farris, III, MD

352 Glomerulonephritis of Chronic Infection, Including

Shunt Nephritis

A. Brad Farris, III, MD

354 Endocarditis

A. Brad Farris, III, MD and Christie L. Boils, MD

358 Syphilis

Shane Meehan, MB, BCh

360 Lyme Disease

Neeraja Kambham, MD

362 COVID-19 Nephropathies

Lynn D. Cornell, MD, Mariam Priya Alexander, MD, and Robert B. Colvin, MD

366 Hepatitis B Virus

Anthony Chang, MD

370 Hepatitis C Virus

Anthony Chang, MD and Charles Alpers, MD

376 Hepatitis B Virus

Anthony Chang, MD

380 HIV-Associated Nephropathy

A. Brad Farris, III, MD

386 Miscellaneous HIV-Associated Renal Diseases

A. Brad Farris, III, MD

392 Schistosomiasis

Neeraja Kambham, MD

394 Filariasis

Christie L. Boils, MD and Tiffany Caza, MD

395 Leishmaniasis

Kerstin Amann, MD and Robert B. Colvin, MD

DRUG-INDUCED GLOMERULAR DISEASES

396 Drug-Induced Minimal Change Disease

Anthony Chang, MD and Astrid Weins, MD, PhD

398 Bisphosphonate-Induced Collapsing Glomerulopathy

A. Brad Farris, III, MD and Astrid Weins, MD, PhD

399 Chloroquine Toxicity

Shane Meehan, MB, BCh

400 Antihepatitis C Virus Drugs

Ivy A. Rosales, MD

404 Anti-EGFR Drugs

Kammi J. Henriksen, MD

GENETIC DISEASES OF GLOMERULUS

406 Overview and Classification of Genetic Diseases of Glomerulus

Sanjay Jain, MD, PhD and Yasar Caliskan, MD

408 Genetic Causes of Nephrotic Syndrome

Joseph P. Gaut, MD, PhD

GENETIC DISEASES OF GLOMERULAR BASEMENT MEMBRANE COLLAGEN

412 Alport Syndrome

Joseph P. Gaut, MD, PhD, Helen Liapis, MD, and Robert B. Colvin, MD

424 Thin Basement Membrane Disease

Joseph P. Gaut, MD, PhD and Helen Liapis, MD

GENETIC DISEASES OF PODOCYTE

426 Diffuse Mesangial Sclerosis

Joseph P. Gaut, MD, PhD and Helen Liapis, MD

430 Congenital Nephrotic Syndrome of Finnish Type

Joseph P. Gaut, MD, PhD and Helen Liapis, MD

434 Pierson Syndrome

Joseph P. Gaut, MD, PhD and Helen Liapis, MD

436 Galloway-Mowat Syndrome

Stephen M. Bonsib, MD

438 Denys-Drash Syndrome

Kammi J. Henriksen, MD and Stephen M. Bonsib, MD

442 Frasier Syndrome

Stephen M. Bonsib, MD

446 Podocin Deficiency

Joseph P. Gaut, MD, PhD and Helen Liapis, MD

448 a-Actinin-4 Deficiency

Joseph P. Gaut, MD, PhD and Helen Liapis, MD

450 Autosomal Dominant FSGS Due To INF2 Mutations

Robert B. Colvin, MD

452 APOL1-Related Glomerular Disease

Christopher P. Larsen, MD and Tiffany Caza, MD

456 Schimke Immunoosseous Dysplasia

Shane Meehan, MB, BCh

GENETIC STORAGE AND LIPID DISEASES

458 Fabry Disease

Robert B. Colvin, MD and Laura Barisoni, MD

466 Alagille Syndrome

Anthony Chang, MD

468 Lecithin Cholesterol Acyltransferase Deficiency

Carrie L. Phillips, MD and Stephen M. Bonsib, MD

472 APOE Lipoprotein Glomerulopathy

Joseph P. Gaut, MD, PhD and Helen Liapis, MD

474 Type III Hyperlipoproteinemia

Joseph P. Gaut, MD, PhD and Helen Liapis, MD

476 I-Cell Disease (Mucolipidosis II)

Stephen M. Bonsib, MD

478 Gaucher Glomerulopathy

A. Brad Farris, III, MD

OTHER GENETIC DISEASES AFFECTING GLOMERULUS

480 Type III Collagen Glomerulopathy

Joseph P. Gaut, MD, PhD, L. Nicholas Cossey, MD, FCAP, and Helen Liapis, MD

484 Nail-Patella Syndrome

Joseph P. Gaut, MD, PhD and Helen Liapis, MD

486 Glomerulopathy of Hereditary Multiple Exostoses

Robert B. Colvin, MD and Ian Roberts, MBChB, FRCPath

MISCELLANEOUS GLOMERULAR DISEASES

488 Cryofibrinogenic Glomerulopathy

Lynn D. Cornell, MD and Mariam Priya Alexander, MD

492 IgM Nephropathy

Neeraja Kambham, MD

494 IgG Nephropathy

Anthony Chang, MD

498 Vaccination-Associated Renal Disease

Astrid Weins, MD, PhD and Mariam Priya Alexander, MD

502 Nephropathies in Chronic Liver Diesease, Including Hepatic Glomerulosclerosis

Robert B. Colvin, MD

506 Renal Disease in Rheumatoid Arthritis

Neeraja Kambham, MD

512 Hemophagocytic Glomerulopathy

Lynn D. Cornell, MD

516 Coenzyme-Q Nephropathies

Laura Barisoni, MD

520 Intravascular Large B-Cell Lymphoma

Anthony Chang, MD

SECTION 3: VASCULAR DISEASES

524 Overview and Classification of Systemic Vasculitides

Surya V. Seshan, MD and Ingeborg Bajema, MD

ANCA DISEASES

534 ANCA-Related Glomerulonephritis

Surya V. Seshan, MD and Ingeborg Bajema, MD

540 Microscopic Polyangiitis

Surya V. Seshan, MD and Ingeborg Bajema, MD

548 Granulomatosis With Polyangiitis

Surya V. Seshan, MD and Ingeborg Bajema, MD

558 Eosinophilic Granulomatosis With Polyangiitis

(Churg-Strauss)

Surya V. Seshan, MD and Ingeborg Bajema, MD

564 Drug-Induced ANCA Vasculitis

Surya V. Seshan, MD and Ingeborg Bajema, MD

NON-ANCA VASCULITIDES

568 Polyarteritis Nodosa

Surya V. Seshan, MD

574 Kawasaki Disease

Surya V. Seshan, MD and Yael K Heher, MD

576 Giant Cell Arteritis

Surya V. Seshan, MD

580 Takayasu Arteritis

Surya V. Seshan, MD

584 Hypocomplementemic Urticarial Vasculitis (Anti-C1q Vasculitis)

Robert B. Colvin, MD

THROMBOTIC MICROANGIOPATHIES

586 Introduction to Thrombotic Microangiopathies

Neeraja Kambham, MD and Ivy A. Rosales, MD

592 Hemolytic Uremic Syndrome, Infection Related

Neeraja Kambham, MD and Ivy A. Rosales, MD

598 Thrombotic Microangiopathy, Genetic

Neeraja Kambham, MD and Ivy A. Rosales, MD

602 Thrombotic Microangiopathy, Autoimmune

Neeraja Kambham, MD and Ivy A. Rosales, MD

606 Thrombotic Microangiopathy, Drugs

Neeraja Kambham, MD and Ivy A. Rosales, MD

610 Postpartum Hemolytic Uremic Syndrome

Neeraja Kambham, MD and Ivy A. Rosales, MD

614 Scleroderma Renal Disease

Neeraja Kambham, MD and Ivy A. Rosales, MD

620 Multicentric Castleman Disease

Lynn D. Cornell, MD

OTHER DISEASES AFFECTING ENDOTHELIUM

622 Preeclampsia, Eclampsia, HELLP Syndrome

Anthony Chang, MD

624 Radiation Nephropathy

Anthony Chang, MD

626 Sickle Cell Nephropathy

Anthony Chang, MD

630 Retinal Vasculopathy and Cerebral Leukodystrophy

Robert B. Colvin, MD

HYPERTENSIVE RENAL DISEASE

632 Hypertensive Renovascular Disease

A. Brad Farris, III, MD

640 Renal Artery Stenosis

A. Brad Farris, III, MD

644 Fibromuscular Dysplasia

A. Brad Farris, III, MD

650 Neurofibromatosis

Kammi J. Henriksen, MD and Stephen M. Bonsib, MD

THROMBOTIC AND EMBOLIC DISEASE

654 Renal Vein Thrombosis

Anthony Chang, MD and Yael K Heher, MD

656 Renal Artery Thrombosis

Anthony Chang, MD

658 Atheromatous Emboli

Anthony Chang, MD

660 Hydrophilic Polymer Emboli

Kammi J. Henriksen, MD

SECTION 4: TUBULOINTERSTITIAL DISEASES

664 Overview and Classification of Tubulointerstitial Diseases

Robert B. Colvin, MD

666 Differential Diagnosis of Acute Interstitial Nephritis

Lynn D. Cornell, MD

672 Granulomatous Interstitial Nephritis

Ivy A. Rosales, MD

676 Guide to Crystal Nephropathies

ISCHEMIC INJURY

680 Acute Tubular Injury

Shane Meehan, MB, BCh

686 Renal Cortical Necrosis

Shane Meehan, MB, BCh

688 Sepsis/Shock

Joseph P. Gaut, MD, PhD

IMMUNOLOGIC TUBULAR DISEASES

690 IgG4-Related Disease

Lynn D. Cornell, MD

700 Sjögren Syndrome

Josephine M. Ambruzs, MD, MPH

704 Tubulointerstitial Nephritis With Uveitis

A. Brad Farris, III, MD

708 Sarcoidosis

Josephine M. Ambruzs, MD, MPH

712 Antibrush Border Autoantibody Tubulointerstitial Nephritis

Ivy A. Rosales, MD and Robert B. Colvin, MD

714 Anti-Tubular Basement Membrane Disease

Robert B. Colvin, MD

716 Idiopathic Hypocomplementemic Tubulointerstitial Nephritis

Lynn D. Cornell, MD

720 Tubulointerstitial Nephritis With IgM(+) Plasma Cells

Lynn D. Cornell, MD

722 Giant Cell Tubulitis With TBM Deposits

Anthony Chang, MD

MONOCLONAL IMMUNOGLOBULIN DISEASES OF TUBULOINTERSTIITIUM

724 Light Chain Cast Nephropathy

Anthony Chang, MD and Kammi J. Henriksen, MD

730 Light Chain Proximal Tubulopathy With Crystals

Lynn D. Cornell, MD

734 Light Chain Proximal Tubulopathy Without Crystals

Christopher P. Larsen, MD and Tiffany Caza, MD

738 Crystal-Storing Histiocytosis

Mariam Priya Alexander, MD

DRUG-INDUCED TUBULOINTERSTITIAL DISEASES

742 Drug-Induced Acute Interstitial Nephritis

Lynn D. Cornell, MD and Robert B. Colvin, MD

748 Drugs That Cause Tubulointerstitial Nephritis

Robert B. Colvin, MD and Lynn D. Cornell, MD

750 Checkpoint Inhibitor-Induced Kidney Diseases

Ivy A. Rosales, MD

754 Papillary Necrosis

Neeraja Kambham, MD

758 Cisplatin Nephrotoxicity

Shane Meehan, MB, BCh

760 Osmotic Tubulopathy

Shane Meehan, MB, BCh and Evan Farkash, MD, PhD

764 Antiviral Drug Nephrotoxicity

Shane Meehan, MB, BCh

770 Acute Phosphate Nephropathy

Lynn D. Cornell, MD

772 Lithium-Induced Renal Disease

Anthony Chang, MD and Yael K Heher, MD

774 Calcineurin Inhibitor Toxicity

Shane Meehan, MB, BCh

780 mTOR Inhibitor Toxicity

Lynn D. Cornell, MD

782 Vancomycin-Induced Cast Nephropathy

Kammi J. Henriksen, MD

784 Anticoagulant-Related Nephropathy

Christopher P. Larsen, MD and Tiffany Caza, MD

786 Illicit Drugs and Opioids

Kammi J. Henriksen, MD

TOXIC INJRY

788 Myoglobinuria/Rhabdomyolysis/Hemoglobinuria

Neeraja Kambham, MD

790 Bile Cast Nephropathy

Anthony Chang, MD

792 Lead and Other Heavy Metal Toxins

Shane Meehan, MB, BCh

796 Ethylene Glycol Toxicity

Shane Meehan, MB, BCh

798 Aristolochic Acid Nephropathy

Shane Meehan, MB, BCh

800 Balkan Endemic Nephropathy

Shane Meehan, MB, BCh

802 Argyria

Robert B. Colvin, MD

AUTOSOMAL DOMINANT TUBULOINTERSTITIAL KIDNEY DISEASE

804 MUC1-Related Autosomal Dominant Tubulointerstitial Kidney Disease

Joseph P. Gaut, MD, PhD and Helen Liapis, MD

806 UMOD-Related Autosomal Dominant Tubulointerstitial Kidney Disease

Shane Meehan, MB, BCh

808 REN-Related Autosomal Dominant Tubulointerstitial Kidney Disease

Lynn D. Cornell, MD

810 HNF1B-Related Autosomal Dominant Tubulointerstitial Kidney Disease

Robert B. Colvin, MD and Marie Claire Gubler, MD

GENETIC CRYSTAL DEPOSITION DISEASES

812 Uric Acid Nephropathy/Gout

Shane Meehan, MB, BCh

816 Primary Hyperoxaluria

Shane Meehan, MB, BCh

818 2,8-Dihydroxyadeninuria

Lynn D. Cornell, MD

820 Cystinosis

Joseph P. Gaut, MD, PhD and Helen Liapis, MD

GENETIC TRANSPORT DISEASES

822 Bartter Syndrome

Shane Meehan, MB, BCh

824 Dent Disease

Lynn D. Cornell, MD

826 Oculocerebrorenal Syndrome of Lowe

Josephine M. Ambruzs, MD, MPH

OTHER GENETIC DISEASES AFFECTING TUBULES

828 Mitochondriopathies

Surya V. Seshan, MD and Laura Barisoni, MD

832 Systemic Karyomegaly

Robert B. Colvin, MD

834 Methylmalonic Acidemia

Lynn D. Cornell, MD and Linda Hasadsri, MD, PhD

MISCELLANEOUS TUBULOINTERSTITIAL DISEASES

838 Nephrocalcinosis

Lynn D. Cornell, MD

840 Secondary Oxalosis

Lynn D. Cornell, MD

842 Chronic Interstitial Nephritis in Agricultural

Communities

Lynn D. Cornell, MD

844 Extramedullary Hematopoiesis

Lynn D. Cornell, MD

848 Mastocytosis

R. Neal Smith, MD

SECTION 5: INFECTIONS OF KIDNEY

BACTERIAL INFECTIONS OF KIDNEY

854 Acute Pyelonephritis

Neeraja Kambham, MD

862 Chronic Pyelonephritis

Neeraja Kambham, MD

866 Xanthogranulomatous Pyelonephritis

Neeraja Kambham, MD and Ivy A. Rosales, MD

870 Malakoplakia

Neeraja Kambham, MD

874 Tuberculosis

Neeraja Kambham, MD

876 BCG Granulomatous Interstitial Nephritis

Neeraja Kambham, MD

878 Leprosy

Neeraja Kambham, MD

879 Megalocytic Interstitial Nephritis

Neeraja Kambham, MD

880 Nocardiosis

Neeraja Kambham, MD

882 Leptospirosis

Shane Meehan, MB, BCh

884 Whipple Disease

Carrie L. Phillips, MD

FUNGAL, RICKETTSIAL, AND PARASITIC INFECTIONS OF KIDNEY

886 Mucormycosis

Anthony Chang, MD

888 Candidiasis

Anthony Chang, MD

889 Histoplasmosis

Anthony Chang, MD

890 Coccidioidomycosis

Anthony Chang, MD

891 Blastomycosis

Anthony Chang, MD

892 Paracoccidioidomycosis

Anthony Chang, MD

893 Aspergillosis

Anthony Chang, MD

894 Cryptococcosis

Anthony Chang, MD

895 Microsporidiosis

Robert B. Colvin, MD

896 Rickettsial Infections

Shane Meehan, MB, BCh

898 Toxoplasmosis

Neeraja Kambham, MD

900 Hydatidosis

Stephen M. Bonsib, MD

VIRAL INFECTIONS OF KIDNEY

902 Polyomavirus Nephritis

Anthony Chang, MD and Evan Farkash, MD, PhD

910 Cytomegalovirus Infection

Anthony Chang, MD and R. Neal Smith, MD

912 Adenovirus Infection

Anthony Chang, MD and R. Neal Smith, MD

914 Epstein-Barr Virus Nephritis

Anthony Chang, MD and R. Neal Smith, MD

916 Herpes Simplex Acute Nephritis

Anthony Chang, MD and R. Neal Smith, MD

918 Hantavirus Nephropathy

A. Brad Farris, III, MD

SECTION 6: DEVELOPMENTAL DISEASES

922 Overview of Congenital Anomalies of Kidney and Urinary Tract

Sanjay Jain, MD, PhD

926 Dysplasia/Hypoplasia/Agenesis

Sanjay Jain, MD, PhD

932 Oligomeganephronia

Robert B. Colvin, MD and Yael K Heher, MD

934 Ectopia, Malrotation, Duplication, Fusion, Supernumerary Kidney

Sanjay Jain, MD, PhD

938 Ask-Upmark Kidney

Lynn D. Cornell, MD

940 Renal Tubular Dysgenesis

Stephen M. Bonsib, MD

SECTION 7: CYSTIC DISEASES

946 Overview of Cystic Diseases

Joseph P. Gaut, MD, PhD, Helen Liapis, MD, and Stephen M. Bonsib, MD

CILIOPATHIES

952 Autosomal Dominant Polycystic Kidney Disease

Anthony Chang, MD, Robert B. Colvin, MD, and Yael K Heher, MD

958 Autosomal Recessive Polycystic Kidney Disease

Stephen M. Bonsib, MD

964 Nephronophthisis and Related Ciliopathies

Kerstin Amann, MD, Helen Liapis, MD, and Robert B. Colvin, MD

OTHER GENETIC CYSTIC DISEASES

970 von Hippel-Lindau Disease

Stephen M. Bonsib, MD

976 Tuberous Sclerosis Complex

Christie L. Boils, MD

982 Zellweger Syndrome

Stephen M. Bonsib, MD

MISCELLANEOUS CYSTIC DISEASES

984 Medullary Sponge Kidney

Lynn D. Cornell, MD and Aleksandr Vasilyev, MD, PhD

986 Mixed Epithelial and Stromal Tumor Family

Stephen M. Bonsib, MD

992 Pediatric Cystic Nephroma

Angelica R. Putnam, MD and Carrie L. Phillips, MD

996 Acquired Cystic Disease

Stephen M. Bonsib, MD and Aleksandr Vasilyev, MD, PhD

1000 Simple and Miscellaneous Cysts

Anthony Chang, MD

1002 Renal Lymphangioma/Lymphangiectasia

Stephen M. Bonsib, MD and Aleksandr Vasilyev, MD, PhD

SECTION 8: DISEASES OF COLLECTING SYSTEM

1008 Introduction to Impediments to Urine Flow

Sanjay Jain, MD, PhD

1012 Reflux Nephropathy

Sanjay Jain, MD, PhD

1016 Obstructive Uropathy

Sanjay Jain, MD, PhD

1020 Nephrolithiasis

Shane Meehan, MB, BCh

1026 Loin Pain Hematuria Syndrome

Stephen M. Bonsib, MD and Xin Gu, MD

SECTION 9: DISEASES OF RENAL ALLOGRAFT

1030 Pathologic Classification of Renal Allograft Diseases

Robert B. Colvin, MD

INTRODUCTION


1032 Evaluation of Allograft Kidney

Lynn D. Cornell, MD and Evan Farkash, MD, PhD

1038 Evaluation of Donor Kidney

Lynn D. Cornell, MD and Evan Farkash, MD, PhD

REJECTION

1044 Acute T-Cell-Mediated Rejection

Lynn D. Cornell, MD and Michael Mengel, MD

1056 Chronic T-Cell-Mediated Rejection

Lynn D. Cornell, MD and Michael Mengel, MD

1060 Hyperacute Rejection

Lynn D. Cornell, MD and Michael Mengel, MD

1064 Acute Antibody-Mediated Rejection

Lynn D. Cornell, MD and Michael Mengel, MD

1072 Chronic Antibody-Mediated Rejection

Lynn D. Cornell, MD and Michael Mengel, MD

1084 Transcript Analysis of Renal Transplant Biopsies

Michael Mengel, MD and R. Neal Smith, MD

RECURRENT AND DE NOVO DISEASES

1088 Diseases That Recur in Allografts

Anthony Chang, MD, Lynn D. Cornell, MD, and R. Neal Smith, MD

1094 De Novo Focal Segmental Glomerulosclerosis

Anthony Chang, MD and Astrid Weins, MD, PhD

1096 De Novo Membranous Glomerulonephritis

Anthony Chang, MD

1100 Anti-GBM Disease in Alport Syndrome

Anthony Chang, MD and R. Neal Smith, MD

1102 Engraftment Syndrome/Chimerism Transition Syndrome

A. Brad Farris, III, MD

1104 Late Post-Transplant Histology

Lynn D. Cornell, MD

OTHER ALLOGRAFT DISEASES

1108 Acute Allograft Ischemia

A. Brad Farris, III, MD

1112 Size Mismatch Allograft Injury

Anthony Chang, MD and Yael K Heher, MD

1114 Urine Leak

A. Brad Farris, III, MD

1115 Lymphocele

A. Brad Farris, III, MD

1116 Transplant Renal Artery Stenosis

A. Brad Farris, III, MD

1118 Tranplant Renal Artery or Vein Thrombosis

A. Brad Farris, III, MD

1120 Posttransplant Lymphoproliferative Disease

A. Brad Farris, III, MD

1130 BK Polyomavirus Neoplasia

Evan Farkash, MD, PhD

1132 Protocol Biopsies

Lynn D. Cornell, MD and Evan Farkash, MD, PhD

1136 Accommodation

Lynn D. Cornell, MD

1138 Tolerance

Robert B. Colvin, MD

1142 Kidney Xenografts

Ivy A. Rosales, MD

KIDNEY PATHOLOGY IN RECIPIENTS OF OTHER TRANSPLANTS

1146 Kidney Diseases in Nonrenal Transplant Recipients

Robert B. Colvin, MD

1150 Graft-vs.-Host Glomerulopathies

Anthony Chang, MD and Yael K Heher, MD

SECTION 10: KIDNEY EXAMINATION

1154 Examination of End-Stage Kidney

Shane Meehan, MB, BCh

1160 Examination of Tumor Nephrectomy Specimens for Nonneoplastic Diseases

Kammi J. Henriksen, MD and Stephen M. Bonsib, MD

1164 Evaluation of Transplant Nephrectomy

Shane Meehan, MB, BCh and Evan Farkash, MD, PhD

1168 Evaluation of Autopsy Kidneys

Kammi J. Henriksen, MD and Mariam Priya Alexander,MD

SECTION 11: TECHNIQUES

1174 Kidney Biopsy Reports

Surya V. Seshan, MD, Anthony Chang, MD, and Lynn D. Cornell, MD

1176 Needle Biopsy: Evaluation for Adequacy

Lynn D. Cornell, MD

1180 Artificial Intelligence and Digital Pathology Analysis

of Interstitium Tubules Vessels

A. Brad Farris, III, MD

1184 Evaluation of Fibrosis

A. Brad Farris, III, MD

1188 Image Analysis of Glomerular Disease Measurement of GBM Thickness and Podocyte Effacement

Laura Barisoni, MD

1192 Immunofluorescence on Paraffin Tissue Sections

Nidia Messias, MD

1196 EM Processing From Paraffin Tissue

A. Brad Farris, III, MD

1198 Detection of Autoantigens in Mebranous Nephropathy

Christopher P. Larsen, MD and A. Bernard Collins, BS

1200 Alport Collagen IV Immunofluorescence

Robert B. Colvin, MD and A. Bernard Collins, BS

1202 C4d Immunohistochemistry/Immunofluorescence

Robert B. Colvin, MD and A. Bernard Collins, BS

1206 Polyomavirus Detection in Tissue

Robert B. Colvin, MD

1208 Mass Spectrometry

Sanjeev Sethi, MD and Mariam Priya Alexander, MD

1210 Diagnostic Genetics of Kidney Diseases

Sanjay Jain, MD, PhD and Yasar Caliskan, MD

1214 Quality Analysis in Renal Pathology

Yael K Heher, MD

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