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Zipes and Jalife’s Cardiac Electrophysiology: From Cell to Bedside,8/e

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의학서적전문 "성보의학서적"의 신간의학도서입니다.


Fully updated from cover to cover, Zipes and Jalife’s Cardiac Electrophysiology: From Cell to Bedside, 8th Edition, provides the comprehensive, multidisciplinary coverage you need—from new knowledge in basic science to the latest clinical advances in the field. Drs. José Jalife and William Gregory Stevenson lead a team of global experts who provide cutting-edge content and step-by-step instructions for all aspects of cardiac electrophysiology. 


Key Features


•Packs each chapter with the latest information necessary for optimal basic research as well as patient care. 

•Covers new technologies such as CRISPR, protein research, improved cardiac imaging, optical mapping, and wearable devices. 

•Contains significant updates in the areas of molecular biology and genetics, iPSCs (induced pluripotent stem cells), embryonic stem cells, precision medicine, antiarrhythmic drug therapy,  cardiac mapping with advanced techniques, and ablation technologies including stereotactic radioablation. 

•Includes 47 new chapters covering both basic science and clinical topics. 

•Discusses extensive recent progress in the understanding, diagnosis, and management of arrhythmias, including new clinical insights on atrial fibrillation and stroke prevention, new advances in the understanding of ventricular arrythmias in genetic disease, and advances in implantable devises and infection management. 

•Features 1,600 high-quality photographs, anatomic and radiographic images, electrocardiograms, tables, algorithms, and more., with additional figures, tables, and videos online. 

•Recipient of a 2018 Highly Commended award from the British Medical Association. 

•Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.


Author Information


By Jose Jalife, MD, Cyrus and Jane Farrehi Professor of Cardiovascular Research, Department of Internal Medicine, Professor of Molecular and Integrative Physiology, Co-Director for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan; Senior Investigator, Fundacion Centro Nacional De Investigaciones Cardiovascularres (CNIC), Madrid, Spain and William Gregory Stevenson, MD, Director, Cardiac Arrhythmia Program, Cardiovascular Division, Brigham and Women's Hospital; Professor of Medicine Harvard Medical School, Boston, MA


- 도서목차-


1 Voltage-Gated Sodium Channels and Electrical Excitability of the Heart

 2 Voltage-Gated Calcium Channels

 3 Voltage-Regulated Potassium Channels

 4 Molecular Regulation of Cardiac Inward Rectifier Potassium Channel

 5 Mammalian Calcium Pumps in Health and Disease

 6 Structural and Molecular Bases of Sarcoplasmic Reticulum Ion Channel Function

 7 Organellar Ion Channels and Transporters

 8 Gap Junctional Connexin 43: Novel Insights from the New Millennium and their Clinical Implications

 9 Computational modeling and simulation for human cardiac electrophysiology: From induced pluripotent stem-cell derived cardiomyocytes to adult cardiomyocytes

 10 Regulation of Cardiac Calcium Channels

 11 Molecular Genetics of ATP-Sensitive Potassium Channels in Cardiovascular Diseases

 12 Role of Enhancers in Transcriptional Regulation of Cardiac Electrical Activity

 13 Functional characterization of ion channel gene variants in sudden unexplained natural death

 14 Stretch-Activated Potassium Channels in the Human Heart: Pathophysiologic and Clinical Significance

 15 Connexins and Pannexins in Cardiovascular Disease

 16 Excitation-Contraction Coupling

 17 Ion Channel Trafficking in the Heart

 17 Ion Channel Trafficking in the Heart

 18 Microdomain Interactions of Macromolecular Complexes and Regulation of the Sodium Channel Nav1.5

 19 Connecting Cardiac Excitation to the Atomic Interactions of Ion Channels

 20 Macromolecular Complexes and Cardiac Potassium Channels

 21 Reciprocity of Cardiac Sodium and Potassium Channels in the Control of Excitability and Arrhythmias

 22 The Intercalated Disc: A Molecular Network That Integrates Electrical Coupling, Intercellular Adhesion and Cell Excitability

 23 Function and Dysfunction of Ion Channel Membrane Trafficking and Post Translational Modification

 24 Feedback Mechanisms for Cardiac-Specific microRNAs and cAMP Signaling in Electrical Remodeling

 25 Coupled Oscillators and Sinoatrial Pacemaker Activity

 25 Coupled Oscillators and Sinoatrial Pacemaker Activity

 26 Mapping of Cardiac Action Potentials in Zebrafish to Assess Genetic Variants

 27 Cell-to-Cell Communication and Impulse Propagation

 28 Mechanisms of Normal and Dysfunctional Sinoatrial Nodal Excitability and Propagation

 29 Cell Biology of the Specialized Cardiac Conduction System

 30 Computational Predictions of Drug-Induced Arrhythmias

 31 Global Optimization Approaches to Generate Dynamically Robust Electrophysiological Models

 32 Calcium Signaling in Cardiomyocyte Models with Realistic Geometries

 33 Theory of Rotors and Arrhythmias

 34 Distinct ECG Phenotypes Identified in Hypertrophic Cardiomyopathy Using Machine Learning Associated with Arrhythmic Risk Markers

 35 Computational Approaches for Accurate Rotor localization in the Human Atria

 36 Modeling the Aging Heart

 37 Electromechanical Vortex Filaments During Cardiac Fibrillation

 38 Innervation of the Sinoatrial Node

 39 Autonomic and Oxidant Regulation of Cardiac Sodium Currents: Mechanisms and Consequences

 40 Neural Activity and Atrial Tachyarrhythmias

 41 Sympathetic Modulation of Cardiac Electrophysiology

 42 Role of the Autonomic Nervous System in Atrial Fibrillation

 43 Rotational and Focal Sources of Atrial Fibrillation: Scientific Rationale and Comparative Clinical Mapping

 44 Nonivasive Frequency-Phase Mapping of Atrial Fibrillation

 45 Mechanistic approaches for persistent AF ablation

 46 Mechanisms of Human Ventricular Tachycardia and Human Ventricular Fibrillation

 47 Genetics of Atrial Fibrillation

 48 Mechanisms in Genetic Sodium Channel Diseases

 49 Genetic, Ionic and Cellular Mechanisms Underlying the J Wave Syndromes

 50 Inheritable Potassium Channel Diseases

 51 Inheritable Phenotypes Associated With Altered Intracellular Calcium Regulation

 52 Dominant Frequency as a Tool for Personalized Monitoring of Atrial fibrillation Progression and Upstream Therapy

 53 Pharmacogenomics of Cardiac Arrhythmias

 54 Screening Drugs for Myocardial Disease in Vivo with Zebrafish

 55 Gene Therapy for Atrial Fibrillation

 56 Cardiac Remodeling and Regeneration

 57 High-Throughput Optical Mapping of 2-Dimensional hiPSC-CM Platforms for Drug Discovery and Cardiotoxicity Testing

 58 Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors

 59 The challenges of human iPSC-CM technology: Increasingly complex approaches improve cell maturation and relevance to modelling human cardiac disease

 60 Assessment of the Patient With a Cardiac Arrhythmia

 61 Differential Diagnosis of Narrow and Wide Complex Tachycardias

 62 Electrocardiographic Monitoring: Short, Long-Term Recording

 63 Personal Cardiac Monitoring

 64 Computed Tomography for Electrophysiology

 65 Magnetic Resonance Imaging for Electrophysiology

 66 Intracardiac Echocardiography for Electrophysiology

 67 Autonomic Nervous System Assessment for Syncope and Arrhythmia Risk

 68 Noninvasive Electrocardiographic Imaging of Arrhythmogenic Substrates and Arrhythmias

 69 Genetic Testing

 70 Supraventricular Tachycardias: Diagnostic Maneuvers in the Electrophysiology Laboratory

 71 Atrial Tachycardia

 72 Atrioventricular Nodal Reentrant Tachycardia

 73 Junctional Tachycardia

 74 Preexcitation, Atrioventricular Reentry, Variants

 75 Atrial Fibrillation: Mechanisms, Clinical Features, and Management

 76 Ablation for Atrial Fibrillation

 77 Left Atrial Appendage Management

 78 Typical and Atypical Atrial Flutter: Mapping and Ablation

 79 Sudden Cardiac Death in Adults

 80 Premature Ventricular Complexes

 81 Outflow Tract Ventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management

 82 PVC Ablation with Anatomic Guidance: Papillary Muscle, Moderator Band and Valve Annulus Sites

 83 Fascicular Ventricular Arrhythmias

 84 Bundle Branch Reentry Tachycardia

 85 Ischemic Heart Disease

 86 Ablation of Post-Myocardial Infarction Ventricular Tachycardia 

 87 Ventricular Tachycardia in Patients with Dilated Cardiomyopathy

 88 Lamin A/C, Noncompaction and Other Genetic Cardiomyopathies with Ventricular Arrhythmias

 89 Ventricular Arrhythmias in Hypertrophic Cardiomyopathy: Sudden Death, Risk Stratification, and Prevention With Implantable Defibrillators

 90 Ventricular Tachycardias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy

 91 Catecholaminergic Polymorphic Ventricular Tachycardia

 92 Arrhythmias and Conduction Disturbances in Noncompaction Cardiomyopathy

 93 Ventricular Arrhythmias in Takotsubo Cardiomyopathy

 94 Mitral Valve Prolapse, ventricular arrhythmias and Sudden Death

 95 Brugada Syndrome

 96 Long and Short QT Syndromes

 97 Andersen-Tawil Syndrome

 98 Timothy Syndrome

 99 J-Wave Syndromes

 100 Idiopathic and Short-Coupled Ventricular Fibrillation

 101 Mapping and Ablation of Ventricular Fibrillation

 102 Drug-Induced Ventricular Arrhythmias

 103 Syncope

 104 Sinus Node Abnormalities

 105 Postural Orthostatic Tachycardia Syndrome

 106 Atrioventricular Block

 107 Sex Differences in Arrhythmias

 108 Sudden Cardiac Deaths in Athletes, Including Commotio Cordis

 109 Cardiac Sarcoidosis

 110 Sleep-Disordered Breathing and Arrhythmias

 111 Ventricular Assist Devices and Cardiac Transplant Recipients

 112 Arrhythmia in Neurologic Disease

 113 Cancer Therapy Related Arrhythmias

 114 Arrhythmias in the Pediatric Population

 115 Supraventricular Tachycardias in Congenital Heart Disease

 116 Ventricular Arrhythmias in Congenital Heart Disease

 117 Antiarrhythmic Drugs

 118 Impact of Nontraditional Antiarrhythmic Drugs on Sudden Cardiac Death

 119 Oral Anticoagulants

 120 Implantable Pacemakers

 121 Implantable Cardioverter Defibrillators: Technical Aspects

 122 Transvenous Implantable Cardioverter Defibrillator: Clinical Aspects

 123 Subcutaneous Implantable Cardioverter Defibrillators

 124 Wearable Defibrillators

 125 Cardiac Resynchronization

 126 Management of Implanted Device Infections

 127 Electrogram Recording and Signal Processing

 128 Electroanatomic Mapping for Arrhythmias

 129 Mapping Scar-Related Arrhythmias

 130 Radiofrequency Ablation

 131 Cryoablation and Other Radiofrequency Alternatives

 132 Transvascular Ethanol Ablation

 133 Cardiac Radioablation

 134 Epicardial Approach in Electrophysiology

 135 Surgery for Atrial Fibrillation and Other Supraventricular Tachycardias

 136 Surgery for Ventricular Arrhythmias

 137 Neuromodulation for the Treatment of Arrhythmias 



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도서명 Zipes and Jalife’s Cardiac Electrophysiology: From Cell to Bedside,8/e
정   가 370,000원
판매가 333,000원
적립금 9,990원 (3%)
저   자 Jose Jalife
출판사 Elsevier
ISBN   9780323757454
출판일 2021.12
판   형 Hardcover
수량 수량증가수량감소
판   수 1408 page
면   수 1408 page
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