의학서적전문 "성보의학서적"의 신간의학도서입니다.


Genome editing is part of almost every step in the drug discovery pipeline, and this book focuses on drug discovery to help academics, researchers, and professionals apply these editing techniques to drug discovery.


-도서목차-


Prelim pages

Contents

Preface ((to follow))

1. Genome editing in drug discovery

2. Historical overview of Genome Editing from bacteria to higher eukaryotes

3. CRISPR Cas: from bacterial adaptive immunity to the swiss army knife of drug discovery

4. Commercial reagents and services for genome editing

5. Computational tools for target design and analysis

6. Genome editing in cellular disease models

7. Utilizing CRISPR/Cas9 technologies for in vivo disease modeling and therapy

8. Pooled CRISPR KO screens for target identification

9. Functional genomics: arrayed CRISPR KO screens

10. Applications of CRISPRi and CRISPRa in drug discovery

11. High throughput targeted mutagenesis by CRISPR-Cas9 base editing

12. Single-cell transcriptomics and epigenomics for CRISPR-mediated perturbation studies

13. DNA repair pathways in the context of therapeutic genome editing

14. DNA base editing strategies for genome editing

15. RNA base editing technologies for gene therapy

16. Genome Editing applications in cancer T Cell Therapy

17. Genome-editing applications in stem cell engineering and regenerative medicine

18. Delivery and Formulation Methods for Therapeutic Genome Editing

19. Safety aspects of genome editing: Immunogenicity

20. Specificity of CRISPR-Cas9 gene editing

21. Key socio-economic and (bio)ethical challenges in the crispr-cas9 patent landscape

22. Future prospects and emerging technologies for genome editing

Subject Index



기타 의학도서에 관련된 문의사항은 고객센터(02-854-2738) 또는 저희 성보의학서적 홈페이지내 도서문의 게시판에 문의바랍니다.
감사합니다.
성보의학서적 "http://www.medcore.kr