Through five highly regarded editions, Ophthalmology, by Drs. Myron Yanoff and Jay S. Duker, has remained one of the premier texts in the field, providing authoritative guidance on virtually any ophthalmic condition and procedure you may encounter. The fully revised, 6th edition of this award-winning title continues to offer detailed, superbly illustrated content from cover to cover, with extensive updates throughout to keep you current with the latest advancements and fundamentals throughout every subspecialty area in the field. An easy-to-follow, templated format, convenient single volume, and coverage of both common and rare disorders make this title a must-have resource no matter what your level of experience.
Key Features
Offers truly comprehensive coverage, including basic foundations through diagnosis and treatment advances across all subspecialties: genetics, optics, refractive surgery, lens and cataract, cornea, retina, uveitis, tumors, glaucoma, neuro-ophthalmology, pediatric and adult strabismus, and oculoplastics.
Features streamlined, templated chapters, a user-friendly visual layout, and key features boxes for quick access to clinically relevant information and rapid understanding of any topic.
Contains four new chapters covering Phototherapeutic Keratectomy; IOL Optics; Bag-in-the-lens Cataract Surgery; and Capsulectomy: Modern devices apart from FLACS.
Includes a fully revised and updated chapter on refractive surgery screening and corneal imaging, as well as an expanded chapter on corneal cross-linking.
Provides up-to-date information on the latest advances in the field, including new therapies for retinoblastoma, such as intravenous and intraarterial chemotherapy; less common retinal tumor simulators of retinoblastoma; OCT-Angiography; glaucoma stents; new drug delivery platforms; IOL optics; phototherapeutic keratectomy; intraocular pressure monitoring; and more.
Includes more than 2,000 high-quality illustrations and an expanded video library with more than 60 clips of diagnostic and surgical techniques, including new videos of nystagmus.
Contains updated management guidelines for central retinal artery occlusions (CRAO).
Provides fresh perspectives from new section editors Drs. Carol Shields and Sumit (Sam) Garg.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Author Information
Edited by Myron Yanoff, MD, Professor and Chair, Department of Ophthalmology, Drexel University College of Medicine; Adjunct Professor of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania and Jay S. Duker, MD, Director, New England Eye Center, Chairman and Professor of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts
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Part 1: Genetics 1.1 Fundamentals of Human Genetics 1.2 Molecular Genetics of Selected Ocular Disorders 1.3 Genetic Testing and Genetic Counseling Part 2: Optics and Refraction 2.1 Light 2.2 Optics of the Human Eye 2.3 Clinical Refraction 2.4 Correction of Refractive Errors 2.5 Ophthalmic Instruments 2.6 Wavefront Optics and Aberrations of the Eye Part 3: Refractive Surgery 3.1 Current Concepts, Classification, and History of Refractive Surgery 3.2 Preoperative Evaluation for Refractive Surgery 3.3 Excimer Laser Surface Ablation: Photorefractive Keratectomy (PRK), Laser Subepithelial Keratomileusis (LASEK) and Epi-LASIK 3.4 Laser in Situ Keratomileusis (LASIK) 3.5 Small Incision Lenticule Extraction 3.6 Wavefront and Topography-Based Excimer Laser Refractive Surgery 3.7 Phakic Intraocular Lenses 3.8 Intrastromal Corneal Ring Segments: Synthetic and Cairs 3.9 Surgical Treatment of Presbyopia 3.10 Excimer Laser Phototherapeutic Keratectomy 3.11 Corneal Cross-Linking Part 4: Cornea and Ocular Surface Diseases Section 1: Basic Principles 4.1 Cornea and Ocular Surface Diseases 4.2 Anterior Segment Imaging Modalities Section 2: Congenital Abnormalities 4.3 Congenital Corneal Anomalies Section 3: External Diseases 4.4 Blepharitis 4.5 Herpes Zoster Ophthalmicus Section 4: Conjunctival Diseases 4.6 Conjunctivitis: Infectious and Noninfectious 4.7 Allergic Conjunctivitis 4.8 Tumors of the Conjunctiva 4.9 Pterygium and Conjunctival Degenerations 4.10 Ocular Cicatricial Pemphigoid/Mucous Membrane Pemphigoid Section 5: Scleral and Episcleral Diseases 4.11 Episcleritis and Scleritis Section 6: Corneal Diseases 4.12 Bacterial Keratitis 4.13 Fungal Keratitis 4.14 Parasitic Keratitis 4.15 Herpes Simplex Keratitis 4.16 Peripheral ulcerative keratitis 4.17 Noninfectious Keratitis 4.18 Keratoconus and Other Ectasias 4.19 Anterior Corneal Dystrophies 4.20 Stromal Corneal Dystrophies 4.21 Corneal Endothelium 4.22 Corneal Degenerations 4.23 Dry Eye Disease Section 7: Miscellaneous Conditions 4.24 Complications of Contact Lens Wear 4.25 Corneal and External Eye Manifestations of Systemic Disease Section 8: Trauma 4.26 Acid and Alkali Burns Section 9: Surgery 4.27 Endothelial Keratoplasty: Targeted treatment for corneal endothelial dysfunction 4.28 Penetrating Keratoplasty 4.29 Deep Anterior Lamellar Keratoplasty 4.30 Superficial Corneal Procedures with corneal crosslinking 4.31 Artificial Cornea (Keratoprosthetics) 4.32 Conjunctival Surgery 4.33 Surgical Ocular Surface Reconstruction 4.34 Management of Corneal Thinning, Melting, and Perforation Part 5: The Lens 5.1 Basic Science of the Lens 5.2 Evolution of Intraocular Lens Implantation 5.3 IOL Optics 5.4 Bag-in-the-Lens Cataract Surgery 5.5 Epidemiology, Pathophysiology, Causes, Morphology, and Visual Effects of Cataract 5.6 Patient Workup for Cataract Surgery 5.7 Intraocular Lens Power Calculations 5.8 Indications for Lens Surgery/Indications for Application of Different Lens Surgery Techniques 5.9 The Pharmacotherapy of Cataract Surgery 5.10 Anesthesia for Cataract Surgery 5.11 Phacoemulsification Fluidics 5.12 Refractive Aspects of Cataract Surgery 5.13 Small Incision and Femtosecond Laser-Assisted Cataract Surgery 5.14 Capsulectomy: Modern devices Apart from FLACS 5.15 Manual Cataract Extraction 5.16 Combined Procedures 5.17 Cataract Surgery in Complex Eyes 5.18 Pediatric Cataract Surgery 5.19 Complications of Cataract Surgery 5.20 Secondary Cataract 5.21 Outcomes of Cataract Surgery Part 6: Retina and Vitreous Section 1: Anatomy 6.1 Structure of the Neural Retina and Retinal Pigment Epithelium 6.2 Retinal and Choroidal Circulation Section 2: Ancillary Tests 6.3 Contact B-Scan Ultrasonography 6.4 Camera Based Ancillary Retinal Testing: Autofluorescence, Fluorescein and Indocyanine Green Angiography 6.5 OCT in Retinal Imaging 6.6 Optical Coherence Tomography Angiography 6.7 Retinal Electrophysiology Section 3: Basic Principles of Retinal Surgery 6.8 Light and Laser Injury 6.9 Scleral Buckling Surgery 6.10 Vitrectomy 6.11 Intravitreal Injections and Medication implants Section 4: Dystrophies 6.12 Progressive and “Stationary Inherited Retinal Degenerations 6.13 Inherited Retinal Disease Section 5: Vascular Disorders 6.14 Hypertensive Retinopathy 6.15 Retinal Arterial Obstruction 6.16 Venous Occlusive Disease of the Retina 6.17 Retinopathy of Prematurity 6.18 Diabetic Retinopathy 6.19 Ocular Ischemic Syndrome 6.20 Hemoglobinopathies 6.21 Coats' Disease and Macular Telangiectasia 6.22 Radiation Retinopathy and Papillopathy 6.23 Retinal Arterial Macroaneurysms Section 6: Macular Disorders 6.24 Age-related Macular Degeneration 6.25 Secondary Causes of Choroidal Neovascularization 6.26 Central Serous Chorioretinopathy 6.27 Macular Hole 6.28 Epiretinal Membrane 6.29 Vitreomacular Traction 6.30 Cystoid Macular Edema Section 7: Retinal Detachment 6.31 Retinal Breaks and Other Peripheral Retinal Lesions 6.32 Rhegmatogenous Retinal Detachment 6.33 Serous Detachments of the Neural Retina 6.34 Suprachoroidal Hemorrhage 6.35 Proliferative Vitreoretinopathy Section 8: Trauma 6.36 Posterior Segment Ocular Trauma 6.37 Distant Trauma with Posterior Segment Effects 6.38 Retinal Toxicity of Systemically Administered Drugs Part 7: Uveitis and Other Intraocular Inflammations Section 1: Basic Principles 7.1 Anatomy of the Uvea 7.2 General Approach to the Uveitis Patient and Treatment Strategies Section 2: Infectious Causes of Uveitis—Viral 7.3 Herpetic Viral Uveitis 7.4 Non-herpetic viral infections: West Nile, Chikungunya, Zika, Ebola, HTLV 1, Measles, Rubella Section 3: Infectious Causes of Uveitis-Bacterial 7.5 Syphilitic and Other Spirochetal Uveitis 7.6 Tuberculosis, Leprosy and Brucellosis 7.7 Bartonella-related Infectious Uveitis (Cat Scratch disease) and Whipple's Disease 7.8 Infectious Endophthalmitis Section 4: Infectious Causes of Uveitis--Fungal 7.9 Histoplasmosis 7.10 Fungal Endophthalmitis Section 5: Infectious Causes of Uveitis--Protozoal and Parasitic 7.11 Ocular Toxoplasmosis 7.12 Posterior Parasitic Uveitis Section 6: Uveitis Associated with Systemic Disease 7.13 Uveitis Related to HLA-B27 and Juvenile Idiopathic Arthritis-Associated Uveitis 7.14 Sarcoidosis 7.15 Behçet's disease 7.16 Vogt-Koyanagi-Harada Disease Section 7: Traumatic Uveitis 7.17 Phacogenic Uveitis 7.18 Sympathetic Uveitis Section 8: Uveitis of Unknown Causes 7.19 Idiopathic and Other Anterior Uveitis Syndromes 7.20 Pars Planitis and Other Intermediate Uveitides 7.21 Posterior Uveitis of Unknown Cause-White Spot Syndromes Section 9: Masquerade Syndromes 7.22 Masquerade Syndromes: Neoplasms Part 8: Intraocular Tumors 8.1 Tumors of the Retina and Optic Disc 8.2 Tumors of the Uvea 8.3 Tumors (Solid and Cystic) of the Pigmented and Non-Pigmented Epithelium 8.4 Phakomatoses Part 9: Neuro-ophthalmology Section 1: Imaging in Neuro-Ophthalmology 9.1 Principles of Imaging in Neuro-Ophthalmology 9.2 Optical Coherence Tomography in Neuro-Ophthalmology Section 2: The Afferent Visual System 9.3 Anatomy and Physiology 9.4 Differentiation of Optic Nerve from Macular Retinal Disease 9.5 Congenital Optic Disc Anomalies 9.6 Papilledema and Raised Intracranial Pressure 9.7 Inflammatory Optic Neuropathies and Neuroretinitis 9.8 Ischemic Optic Neuropathy 9.9 Mitochondrial Optic Neuropathies 9.10 Prechiasmal Pathways - Compression by Optic Nerve and Sheath Tumors 9.11 Traumatic Optic Neuropathies 9.12 Lesions of the Optic Chiasm, Parasellar Region, and Pituitary Fossa 9.13 Lesions of Retrochiasmal Pathways, Higher Cortical Function, and Nonorganic Visual Loss Section 3: The Efferent Visual System 9.14 Disorders of Supranuclear Control of Ocular Motility 9.15 Nuclear and Fascicular Disorders of Eye Movement 9.16 Paresis of Isolated and Multiple Cranial Nerves and Painful Ophthalmoplegia 9.17 Disorders of the Neuromuscular Junction 9.18 Ocular Myopathies 9.19 Nystagmus, Saccadic Intrusions, and Oscillations 9.20 Pupillary Signs of Neuro-Ophthalmic Disease Section 4: The Brain 9.21 Headache and Facial Pain 9.22 Tumors, Infections, Inflammations, and Neurodegenerations Section 5: Neuro-Ophthalmologic Emergencies 9.23 Urgent Neuro-Ophthalmic Disorders 9.24 Trauma, Drugs, and Toxins 9.25 Vascular Disorders 9.26 Electrophysiology Part 10: Glaucoma Section 1: Epidemiology and Mechanisms of Glaucoma 10.1 Epidemiology of Glaucoma 10.2 Screening for Glaucoma 10.3 Mechanisms of Glaucoma Section 2: Evaluation and Diagnosis 10.4 Clinical Examination of Glaucoma 10.5 Visual Fields 10.6 Optic Nerve Analysis 10.7 Optic Nerve Blood Flow Measurement 10.8 Ocular Hypertension Section 3: Specific Types of Glaucoma 10.9 Primary Open Angle Glaucoma 10.10 Normal-Tension Glaucoma 10.11 Angle-closure Glaucoma 10.12 Glaucoma Associated with (Pseudo)Exfoliation Syndrome 10.13 Pigmentary Glaucoma 10.14 Neovascular Glaucoma 10.15 Uveitis and Steroid-Induced Ocular Hypertension and Glaucoma 10.16 Glaucoma Associated with Ocular Trauma 10.17 Glaucoma with Elevated Episcleral Venous Pressure 10.18 Aqueous Misdirection 10.19 Glaucomas Secondary to Abnormalities of the Cornea, Iris, Retina, and Intraocular Tumors 10.20 Congenital Glaucoma Section 4: Therapy 10.21 When to Treat Glaucoma 10.22 Current Medical Management of Glaucoma 10.23 Laser Trabeculoplasty and Laser Peripheral Iridectomy 10.24 Cyclodestructive procedures in glaucoma 10.25 Goniotomy and Trabeculotomy 10.26 Micro-invasive Glaucoma Surgeries 10.27 Trabeculectomy 10.28 Antifibrotic Agents in Glaucoma Surgery 10.29 Drainage Implants 10.30 Complications of Glaucoma Surgery and Their Management 10.31 Genes Associated with Human Glaucoma Part 11: Pediatric and Adult Strabismus Section 1: Basic Science 11.1 Anatomy and physiology of the Extraocular Muscles and Surrounding Tissues Section 2: Evaluation and Diagnosis 11.2 Evaluating Vision in Preverbal and Preliterate Infants and Children 11.3 Examination of Ocular Alignment and Eye Movements 11.4 Sensory Status in Strabismus 11.5 Sensory Adaptations in Strabismus Section 3: Ocular Manifestations 11.6 Esotropia 11.7 Exotropia 11.8 Torsional Strabismus 11.9 Paralytic Strabismus 11.10 Other Vertical Strabismus Forms 11.11 Amblyopia Section 4: Treatment 11.12 Forms of Nonsurgical Strabismus Management 11.13 Techniques of Strabismus Surgery Part 12: Orbit and Oculoplastics Section 1: Orbital Anatomy and Imaging 12.1 Clinical Anatomy of the Eyelids 12.2 Clinical Anatomy of the Orbit 12.3 Orbital Imaging Section 2: Eyelids 12.4 Blepharoptosis 12.5 Entropion 12.6 Ectropion 12.7 Benign Eyelid Lesions 12.8 Eyelid Malignancies 12.9 Evaluation and Management of Periorbital Soft Tissue Trauma Section 3: Orbit and Lacrimal Gland 12.10 Orbital Diseases 12.11 Enucleation, Evisceration, and Exenteration 12.12 The Lacrimal Drainage System 12.13 Thyroid Eye Disease 12.14 Orbital Infection and Inflammation Section 4: Periorbital Aesthetic Procedures 12.15 Cosmetic Blepharoplasty and Browplasty 12.16 Aesthetic Fillers and Botulinum Toxin 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