Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery focuses on the emerging hypothesis of a dysfunctional microbiome – metabolome - vagus nerve - brain circuit in Alzheimer’s disease and associated diseases and medical conditions, including dementia, aging, COVID-19, and autoimmune conditions including rosacea. This volume also discusses the vagus nerve-related conditions including Arnold’s reflex, laryngopharyngeal reflux, duodenogastric reflux, gastroesophageal reflux, and related pulmonary diseases. The subjects covered in this book also address an important question: which one is more important for human health and intellectual abilities: the human genome or human microbiome? The conceptual model of food and gut microbial tryptamine - vagus nerve circuit is also presented in this volume.
Addresses the emerging hypothesis of a dysfunctional microbiome - vagus nerve - brain circuit in Alzheimer’s disease and associated diseases and medical conditions Covers dementia, aging, COVID-19, and autoimmune conditions including rosacea Presents the conceptual model of food and gut microbial tryptamine - vagus nerve circuit Covers human health and intellectual abilities in the context of both the human genome and the human microbiome
-도서목차-
1. Introduction: microbial metabolite interference of protein biosynthesis in neurodegenerative, neurodevelopmental and other disorders; microbial metabolites hijacking vagus nerve
2. COVID-19: Scientific Progress
3. Viral-bacterial interactions in diseases
4. Vagus nerve: acid reflux, parietal cells, carpal tunnel syndrome, Alzheimer’s disease, COVID-19, stroke, cancer and other diseases
6. Glutamate, glutamate receptors in vagus nerve pathways and in Alzheimer’s disease
7. Aminoacyl tRNA synthetase multiple forms in autoimmune and infectious diseases
8. Crystalized aromatic L-amino acid decarboxylase from bacteria Micrococcus percitreus catalyzing decarboxylation of tryptophan and L-DOPA (Levodopa or 3,4-dihydroxy-L-phenylalanine)
9. Health effects of elevated CO2 levels, sparkling mineral water, Seltzer carbonated water
10. Microbial antigens, allergies and antibodies to microbial allergens: significance of pre-existing antibodies for vaccination
11. Vagus nerve and taste identification deficits in disease
12. Microorganisms producing biogenic amines: from food to human body
13. Human genome or human microbiome genes: which one is more important for human health and intellectual abilities?
14. Microorganisms used in agriculture, consumed from environment and associated with the edible raw fruits, vegetables, herbs, sprouts, and mushrooms
15. Molecular and cell aggregation: biogenic amines, proteins, platelets and microbial pathogens
16. Colonic diverticular disease as a risk factor for neurodegenerative and associated diseases
17. Alzheimer’s disease, Dementia, Aging and COVID-19
18. Existing vaccines and new and old tools
19. Serotonin syndrome in neurodegenerative diseases and COVID-19: mechanisms and consequences of intestinal infection
20. Circulating cell-free mitochondria and membrane vesicles
21. Protein synthesis inhibition in neuronal activities
22. Rosacea and associated medical disorders
23. Bacterial internalization in cancer and other medical conditions: intracellular pathogens
24. Ocular changes resulting from reading and writing on smartphone and computer: computer vision syndrome, dry eye disease, meibomian gland dysfunction, chalazion, occupational overuse syndrome
25. Viral infections in vagus nerve
26. Microbial Tryptamine in Type 1, Type 2 and Type 3 diabetes
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