Venous Ulcers, Second Edition provides evidence-based data pertinent to genetics and molecular and biochemical mechanisms that lead to the development and progression of venous ulcers. The book summarizes new findings and advances in the field in a clinically applicable way and serves as an updated and comprehensive source for both researchers and medical professionals who need more information on chronic venous insufficiency. During the last two decades, management of venous ulcers has significantly improved. Most notably, our understanding of genetics, pathophysiology and hemodynamic has evolved along with novel diagnostic and treatment modalities in the management of chronic venous insufficiency patients.
Provides detailed understanding of molecular mechanisms that lead to venous ulcerations that can provide fertile environment for scientists for further discoveries Summarizes new findings on etiology, hemodynamics, pathophysiology, diagnosis and treatment of patients with venous ulcers Discusses all currently utilized diagnostic and treatment modalities, as well as provides clear guidelines pertinent to special diagnostic considerations and emerging novel surgical and treatment techniques
1. Pathophysiology of chronic venous disease: Genetic, molecular and biochemical mechanisms 2. Venous hemodynamics and microcirculation in chronic venous insufficiency 3. Venous ulcers of the lower extremity: Etiology, risks and predictive factors 4. Venous ulcers of the lower extremity: Epidemiology and socio-economic burden
Section II: Clinical Evaluation and Diagnostic Modalities
5. Initial clinical evaluation in patients with chronic venous insufficiency 6. Ultrasound evaluation of lower extremity chronic venous disease 7. The diagnosis of major venous outflow obstruction in chronic venous insufficiency 8. Hypercoagulable states associated with chronic venous insufficiency 9. The chronically swollen leg with ulcers - finding the cause: theory and practice 10. Lower extremity wounds associated with mixed venous and arterial insufficiency and relevant differential diagnosis in patients with non-healing wounds of the lower extremity 11. Assessment tools and wound documentation for patients with chronic venous insufficiency
Section III: Non-operative Management of Chronic Venous Insufficiency and Wound Care
12. Compression therapy in venous leg ulcers 13. Wound healing: Adjuvant therapy and treatment adherence 14. Negative pressure dressings in venous ulcers 15. Medical therapies for chronic venous insufficiency 16. Treatment modalities for non-healing wounds in patients with chronic venous insufficiency 17. Deep vein thrombosis and prevention of post-thrombotic syndrome 18. Improving treatment outcomes - Management of coexisting co-morbidities in patients with venous ulcers 19. Emerging modalities in local treatment of venous ulcers: advanced dressings, bioengineering and biologics
Section IV: Operative and Endovascular Procedures for Chronic Venous Insufficiency
20. Results comparing compression alone versus compression and surgery (or endovenous ablation) in treating venous ulceration 21. Superficial surgery and perforator interruption in the treatment of venous leg ulcers 22. Endovascular techniques for superficial vein ablation in treatment of venous ulcers 23. Treatment of chronic venous insufficiency with foam sclerotherapy 24. Ultrasound guidance for endovenous treatment 25. Iliac vein stenting in venous leg ulcers 26. Repair of venous valves in severe chronic venous insufficiency 27. Emerging endovenous modalities in the treatment of chronic venous insufficiency Section V: Special Considerations
28. Treatment of recalcitrant venous ulcers with free tissue transfer for limb salvage 29. Management of venous ulcers in patients with congenital vascular malformations 30. Lymphatic disorders in pathogenesis of chronic venous insufficiency
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