Allergic and Immunologic Diseases: A Practical Guide to the Evaluation, Diagnosis and Management of Allergic and Immunologic Diseases is a valuable resource for researchers and others involved in the day-to-day practice of allergy and immunology, with specific information, protocols and algorithms to guide their thinking. The book provides practical information and an explanation of why and how we do things, while also addressing the limitations of testing and treatment. Other sections focus on scientific based practices and the known pathophysiology of allergic and immunologic diseases, along with mechanisms of action in various treatment modalities. This book is unique in that it explains the rationale behind everything we do in allergy and immunology, hence it offers readers specific information on procedures and how to order tests and treat allergic and immunologic diseases.
Contains useful information on allergic and immunologic diseases, from why we do things the way we do, to methodologies, interpretation of the results and management of diseases Provides information that can be immediately downloadable for any specific procedure or treatment algorithm for immediate use Evaluates scientific merit and evidence or lack thereof
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Section A: Background
1. A history of allergy and immunology 2. The development of clinical laboratory methods in the diagnosis of human disease 3. Discoveries with significant impact in how we diagnosis and treat diseases 4. Taking an allergy and immunology history and physical 5. Basic genetics and epigenetics for the immunologist and allergist 6. Immunological studies – utility and limitations 7. Future developments and how they will impact the practice of medicine
Section B: Diagnosis of allergic diseases
8. Epicutaneous and intradermal skin testing 9. The interpretation of epicutaneous and intradermal skin testing for foods 10. The use of in vitro methods to evaluate allergy 11. Food challenges 12. Testing for the physical urticarias 13. Techniques to evaluate asthma 14. Drug allergy testing 15. Sinus diseases and rhinolaryngoscopy 16. Approach to the rash from an allergy/immunology perspective 17. Patch testing and the evaluation of contact allergy 18. Skin biopsies and their utility 19. The evaluation of mast cell related disorders 20. The evaluation of a patient with urticaria and angioedema 21. Evaluating the patient with eosinophilia or eosinophilic disease 22. Unproven and controversial testing methods in allergy and immunology
Section C: Evaluation of immune function
23. Testing for primary immunodeficiency 24. Testing the innate immune system 25. Testing the adaptive immune system 26. Periodic fever syndromes and autoinflammatory diseases 27. Immunological dysfunction disorders 28. The AIDS workup 29. Basic workup for autoimmune diseases 30. Neuroimmunology 31. Genetic testing
Section D: Treatment of allergic and immunologic diseases
32. Immunotherapy to environmental allergens 33. Drug allergy desensitization methods 34. Oral, sublingual and dermatologic immunotherapy to food allergens 35. Conventional medications for the treatment of allergic diseases 36. The new biologicals in allergy 37. Action plans and quality of life evaluations 38. The treatment of atopic dermatitis 39. The recognition and treatment of anaphylaxis 40. Treatment of venom and other insect allergies 41. Drugs and treatment modalities for itch and hives 42. Integrative medicine in allergy and immunology
Section E: Treatment of immunological disorders
43. Treatment of the patient with PIDD 44. Management of autoinflammatory syndromes and periodic fevers 45. Immunomodulatory pharmaceuticals for the treatment of immune dysfunction 46. Bone marrow transplant for the patient with monogenic PIDD 47. The immunological management of the solid-organ transplant patient 48. Apheresis 49. Pharmaceuticals for AIDS 50. Gene therapy
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