의학서적전문 "성보의학서적"의 신간의학도서입니다.

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of endocrine pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Endocrine is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource.

Key Features
Provides essential knowledge in all areas of endocrine pathology, including thyroid, parathyroid, pituitary, adrenal, paraganglia, pancreas, skin, neuroendocrine neoplasms, and inherited tumor syndromes—more than 150 diagnoses in all

Offers a wealth of new information based on recently recognized and discovered endocrine diseases, as well as tumor types with important implications for patient care

Includes new content on thyroid lesions and tumors now associated with DICER1 gene mutations; the correlation of newly characterized genetic abnormalities in endocrine tumors associated with responses to targeted therapies; and newly recognized syndromes, such as multiple endocrine neoplasia type 4 and type 5, glucagon cell hyperplasia and neoplasia, and others  

Meticulously edited by Dr. Vania Nosé with contributions from renowned pathologists to ensure that common/classic endocrine diagnoses, as well as newly recognized diseases and unusual cases, are well covered

Features nearly 2,000 high-quality clinical and histological images, gross pathology images, radiologic images, and full-color illustrations to help practicing and in-training pathologists reach a confident diagnosis

Includes updated criteria, terminology, and classifications for a wide range of tumors from the upcoming 2021 WHO Classification of Tumors: Endocrine and Neuroendocrine Tumors.

Employs consistently templated chapters, bulleted content, key facts, and annotated images for quick, expert reference at the point of care

Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices


Author Information

By Vania Nosé, MD, PhD, Associate Chief of Pathology, Director of Anatomic and Molecular Pathology, Massachusetts General Hospital, Professor of Pathology, Harvard Medical School, Boston, Massachusetts

-도서목차-


SECTION 1: THYROID

NONNEOPLASTIC

4 Thyroglossal Duct Cyst

Nicole Cipriani, MD and Vania Nosé, MD, PhD

8 Ectopic Thyroid

Vania Nosé, MD, PhD

12 Solid Cell Nests

Vania Nosé, MD, PhD

16 Acute Thyroiditis

Vania Nosé, MD, PhD

20 Granulomatous Thyroiditis (de Quervain)

Vania Nosé, MD, PhD

26 Palpation Thyroiditis

Nicole Cipriani, MD and Vania Nosé, MD, PhD

28 IgG4-Related Thyroid Disease

Vikram Deshpande, MD and Vania Nosé, MD, PhD

32 Riedel Thyroiditis

Vania Nosé, MD, PhD

38 Hashimoto Thyroiditis

Vania Nosé, MD, PhD

46 Graves Disease (Diffuse Hyperplasia)

Suzana Leite, MD and Vania Nosé, MD, PhD

54 Multinodular Thyroid Hyperplasia

Vania Nosé, MD, PhD

58 Dyshormonogenetic Goiter

Vania Nosé, MD, PhD

64 Amyloid Goiter

Vania Nosé, MD, PhD

70 Adenomatous Nodules

Vania Nosé, MD, PhD and Adam Fisch, MD, PhD

76 Pigments and Crystals, Thyroid

Nicole Cipriani, MD and Vania Nosé, MD, PhD

NEOPLASTIC

FOLLICULAR CELL-DERIVED NEOPLASMS

80 Follicular Adenoma

Vania Nosé, MD, PhD and Adam Fisch, MD, PhD

88 Oncocytic (Hurthle Cell) Adenoma

Vania Nosé, MD, PhD and Peter Sadow, MD, PhD

92 Noninvasive Follicular Thyroid Neoplasm With

Papillary-Like Nuclear Features

Vania Nosé, MD, PhD and Ying-Hsia Chu, MD

102 Hyalinizing Trabecular Tumor

Nicole Cipriani, MD and Vania Nosé, MD, PhD

108 Follicular Thyroid Carcinoma

Vania Nosé, MD, PhD and Ying-Hsia Chu, MD

118 Oncocytic (Hurthle Cell) Carcinoma

Ying-Hsia Chu, MD and Vania Nosé, MD, PhD

122 Post-FNA Site Changes, Thyroid

Vania Nosé, MD, PhD and Darcy A Kerr, MD

124 Poorly Differentiated Thyroid Carcinoma

Nicole Cipriani, MD and Vania Nosé, MD, PhD

134 Anaplastic Thyroid Carcinoma

Vania Nosé, MD, PhD and Adam Fisch, MD, PhD

144 Papillary Thyroid Carcinoma

Vania Nosé, MD, PhD and Ying-Hsia Chu, MD

162 Papillary Thyroid Carcinoma, Classic Variant

Vania Nosé, MD, PhD

170 Papillary Thyroid Carcinoma, Encapsulated Follicular

Variant

Vania Nosé, MD, PhD

178 Papillary Thyroid Carcinoma, Follicular Variant,

Infiltrative

Vania Nosé, MD, PhD and Peter Sadow, MD, PhD

182 Papillary Thyroid Carcinoma, Macrofollicular Variant

Vania Nosé, MD, PhD

188 Papillary Thyroid Carcinoma, Diffuse Sclerosing

Variant

Nicole Cipriani, MD and Vania Nosé, MD, PhD

194 Papillary Thyroid Carcinoma, Oncocytic Variant

Vania Nosé, MD, PhD and Peter Sadow, MD, PhD

198 Papillary Thyroid Carcinoma, Tall Cell Variant

Vania Nosé, MD, PhD and Julie Guilmette, MD

206 Papillary Thyroid Carcinoma, Columnar Cell Variant

Vania Nosé, MD, PhD and Peter Sadow, MD, PhD

210 Papillary Thyroid Carcinoma, Clear Cell Variant

Vania Nosé, MD, PhD

212 Papillary Thyroid Carcinoma, Solid Variant

Vania Nosé, MD, PhD and Julie Guilmette, MD

216 Papillary Thyroid Carcinoma, Hobnail Variant

Vania Nosé, MD, PhD

222 Papillary Thyroid Carcinoma, Warthin-Like Variant

Vania Nosé, MD, PhD

228 Cribriform-Morular Carcinoma

Vania Nosé, MD, PhD

238 NTRK-Rearranged Thyroid Carcinoma

Peter Sadow, MD, PhD and Vania Nosé, MD, PhD

244 Kinase Fusion-Related Thyroid Carcinomas

Ying-Hsia Chu, MD and Vania Nosé, MD, PhD

C CELL-DERIVED TUMORS

252 C-Cell Hyperplasia

Vania Nosé, MD, PhD and Adam Fisch, MD, PhD

258 Medullary Thyroid Carcinoma

Vania Nosé, MD, PhD and Adam Fisch, MD, PhD

MIXED MEDULLARY AND FOLLICULAR

CELL CARCINOMA

268 Mixed Medullary and Follicular Cell Carcinoma

Vania Nosé, MD, PhD and Darcy A Kerr, MD

THYMIC TUMORS WITHIN THYROID

272 Ectopic Thymoma

Ying-Hsia Chu, MD and Vania Nosé, MD, PhD

276 Spindle Epithelial Tumor With Thymus-Like

Differentiation

Vania Nosé, MD, PhD

282 Intrathyroid Thymic Carcinoma

Vania Nosé, MD, PhD

SALIVARY GLAND-LIKE THYROID TUMORS

290 Primary Mucoepidermoid Carcinoma of Thyroid

Darcy A Kerr, MD and Vania Nosé, MD, PhD

294 Sclerosing Mucoepidermoid Carcinoma With

Eosinophilia

Vania Nosé, MD, PhD and Darcy A Kerr, MD

300 Primary Secretory Carcinoma

Darcy A Kerr, MD and Vania Nosé, MD, PhD

HEMATOLYMPHOID TUMORS

304 Lymphoma, Thyroid

Vania Nosé, MD, PhD

310 Follicular Dendritic Cell Sarcoma, Thyroid

Vania Nosé, MD, PhD and Darcy A Kerr, MD

314 Langerhans Cell Histiocytosis, Thyroid

Vania Nosé, MD, PhD and Dipti P. Sajed, MD, PhD

GERM CELL ORIGIN

318 Benign Thyroid Teratoma

Vania Nosé, MD, PhD

324 Malignant Thyroid Teratoma

Vania Nosé, MD, PhD and Julie Guilmette, MD

328 Struma Ovarii, Struma Carcinoid, and Malignant

Struma Ovarii

Vania Nosé, MD, PhD

EMBRYONAL THYROID TUMORS

336 Thyroblastoma

Vania Nosé, MD, PhD and Julie Guilmette, MD

MESENCHYMAL AND STROMAL TUMORS

342 Peripheral Nerve Sheath Tumor, Thyroid

Vania Nosé, MD, PhD and Darcy A Kerr, MD

346 Solitary Fibrous Tumor, Thyroid

Dipti P. Sajed, MD, PhD and Vania Nosé, MD, PhD

352 Paraganglioma, Thyroid

Nicole Cipriani, MD and Vania Nosé, MD, PhD

358 Leiomyoma and Leiomyosarcoma, Thyroid

Dipti P. Sajed, MD, PhD and Vania Nosé, MD, PhD

362 Angiosarcoma, Thyroid

Dipti P. Sajed, MD, PhD and Vania Nosé, MD, PhD

366 Primary Ewing Sarcoma, Thyroid

Dipti P. Sajed, MD, PhD and Vania Nosé, MD, PhD

SECONDARY TUMORS WITHIN THYROID

370 Secondary Tumors, Thyroid

Vania Nosé, MD, PhD and Darcy A Kerr, MD

MOLECULAR PATHOLOGY OF THYROID

NEOPLASMS

374 Molecular Pathology of Thyroid Neoplasms

Vania Nosé, MD, PhD and Ying-Hsia Chu, MD

PROTOCOL FOR EXAMINATION OF

SPECIMENS FROM PATIENTS WITH

CARCINOMA OF THYROID GLAND

380 Thyroid Carcinoma Protocol

Vania Nosé, MD, PhD and Julie Guilmette, MD

SECTION 2: PARATHYROID GLAND

NONNEOPLASTIC

384 Primary Chief Cell Hyperplasia

Lori A. Erickson, MD

394 Primary Clear Cell Hyperplasia

Lori A. Erickson, MD

398 Secondary Parathyroid Hyperplasia

Lori A. Erickson, MD

404 Tertiary Parathyroid Hyperplasia

Lori A. Erickson, MD

408 Chronic Parathyroiditis

Lori A. Erickson, MD

NEOPLASTIC

412 Parathyroid Adenoma

Vania Nosé, MD, PhD and Lori A. Erickson, MD

418 Parathyroid Lipoadenoma

Lori A. Erickson, MD

422 Atypical Parathyroid Tumor

Lori A. Erickson, MD

428 Parathyroid Carcinoma

Vania Nosé, MD, PhD and Lori A. Erickson, MD

434 Secondary Tumors, Parathyroid Gland

Lori A. Erickson, MD

SECTION 3: ADRENAL GLANDS

ADRENAL CORTICAL NONNEOPLASTIC

440 Adrenal Heterotopia

Arthur S. Tischler, MD

442 Adrenal Hypoplasia and Malformations

Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD

446 Adrenal Cytomegaly

Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD

448 Adrenal Cortical Hyperplasia

Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD

454 Infectious Disorders, Adrenal Glands

Arthur S. Tischler, MD and Nada A. Farhat, MD, MA, MPH

458 Autoimmune Adrenalitis

Arthur S. Tischler, MD and Nada A. Farhat, MD, MA, MPH

460 Adrenal Amyloidosis

Arthur S. Tischler, MD and Nada A. Farhat, MD, MA, MPH

464 Incidental Adrenal Nodules

Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD

468 Adrenal Cysts

Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD

474 Adrenal Nodular Hyperplasia

Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD

ADRENAL CORTICAL NEOPLASTIC

478 Nonfunctioning Adrenal Cortical Adenomas

Vania Nosé, MD, PhD

480 Aldosterone-Producing Adenomas

Vania Nosé, MD, PhD and Patricia Nogueira de Sa, MD

486 Cortisol-Producing Adenomas

Vania Nosé, MD, PhD

494 Sex Hormone-Producing Adenoma

Vania Nosé, MD, PhD and Peter Sadow, MD, PhD

496 Primary Pigmented Nodular Adrenocortical Disease

Vania Nosé, MD, PhD

502 Adrenal Cortical Oncocytoma

Vania Nosé, MD, PhD and Peter Sadow, MD, PhD

506 Adrenal Cortical Carcinoma

Vania Nosé, MD, PhD and Ying-Hsia Chu, MD

518 Adrenal Cortical Neoplasms in Children

Vania Nosé, MD, PhD and Ying-Hsia Chu, MD

ADRENAL MEDULLA AND PARAGANGLIA

526 Adrenal Medullary Hyperplasia

Vania Nosé, MD, PhD

530 Pheochromocytoma and Paraganglioma

Vania Nosé, MD, PhD, Arthur S. Tischler, MD, and Ying-

Hsia Chu, MD

540 Composite Pheochromocytoma and Composite

Paraganglioma

Vania Nosé, MD, PhD, Arthur S. Tischler, MD, and Ying-

Hsia Chu, MD

546 Neuroblastic Tumors of Adrenal Gland

Vania Nosé, MD, PhD

MESENCHYMAL AND STROMAL TUMORS

558 Myelolipoma

Vania Nosé, MD, PhD

562 Primary Adrenal Malignant Melanoma

Vania Nosé, MD, PhD

566 Primary Adrenal Benign Connective Tissue Tumor

Vania Nosé, MD, PhD

568 Primary Adrenal Angiosarcoma

Vania Nosé, MD, PhD

572 Primary Adrenal Leiomyosarcoma

Vania Nosé, MD, PhD

576 Secondary Tumors, Adrenal Glands

Vania Nosé, MD, PhD

SEX CORD STROMAL TUMORS AND OTHERS

580 Adenomatoid Tumor

Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD

584 Sex Cord Stromal Tumor

Vania Nosé, MD, PhD and Arthur S. Tischler, MD

PROTOCOL FOR EXAMINATION OF

SPECIMENS FROM PATIENTS WITH

CARCINOMA OF ADRENAL GLAND

588 Adrenal Cortical Carcinoma Protocol

Vania Nosé, MD, PhD

SECTION 4: PITUITARY GLAND

NONNEOPLASTIC

592 Hypophysitis, Pituitary Gland

M. Beatriz S. Lopes, MD, PhD

596 Hyperplasia, Pituitary Gland

M. Beatriz S. Lopes, MD, PhD

598 Sarcoidosis, Pituitary Gland

M. Beatriz S. Lopes, MD, PhD and Vania Nosé, MD, PhD

602 Infarction, Pituitary Gland

M. Beatriz S. Lopes, MD, PhD

604 Sheehan Syndrome, Pituitary Gland

M. Beatriz S. Lopes, MD, PhD

606 Cystic Lesions of Sellar Region

M. Beatriz S. Lopes, MD, PhD

610 Empty Sella Syndrome

M. Beatriz S. Lopes, MD, PhD

NEOPLASTIC

ANTERIOR NEUROENDOCRINE

NEOPLASMS

612 Pituitary Adenoma

M. Beatriz S. Lopes, MD, PhD and Vania Nosé, MD, PhD

618 Pituitary Carcinoma

Vania Nosé, MD, PhD and M. Beatriz S. Lopes, MD, PhD

622 Somatotroph Adenoma

M. Beatriz S. Lopes, MD, PhD

626 Lactotroph Adenoma

M. Beatriz S. Lopes, MD, PhD

630 Thyrotroph Adenoma

M. Beatriz S. Lopes, MD, PhD

634 Corticotroph Adenoma

M. Beatriz S. Lopes, MD, PhD

638 Gonadotroph Adenoma

M. Beatriz S. Lopes, MD, PhD

642 Null Cell Adenoma

M. Beatriz S. Lopes, MD, PhD

644 Plurihormonal Adenoma

M. Beatriz S. Lopes, MD, PhD

OTHER ANTERIOR PITUITARY TUMORS

648 Craniopharyngioma, Pituitary Gland

M. Beatriz S. Lopes, MD, PhD

650 Pituitary Blastoma

Vania Nosé, MD, PhD

POSTERIOR PITUITARY CNS NEOPLASMS

654 Posterior Pituitary Tumors: Pituicytoma, Spindle Cell

Oncocytoma, and Granular Cell Tumors

M. Beatriz S. Lopes, MD, PhD

658 Gangliocytoma, Pituitary Gland

M. Beatriz S. Lopes, MD, PhD

662 Neuronal Cell Tumors: Neurocytoma

M. Beatriz S. Lopes, MD, PhD

664 Secondary Tumors, Pituitary Gland

M. Beatriz S. Lopes, MD, PhD

666 Mesenchymal and Hematopoietic Tumors, Pituitary

Gland

M. Beatriz S. Lopes, MD, PhD

670 Protocol for Examination of Specimens From

Patients With Primary Pituitary Tumors

Vania Nosé, MD, PhD and M. Beatriz S. Lopes, MD, PhD

SECTION 5: ENDOCRINE PANCREAS

676 Pancreatic Neuroendocrine Neoplasms

Vania Nosé, MD, PhD

PROTOCOL FOR EXAMINATION OF

SPECIMENS FROM PATIENTS WITH

CARCINOMA OF ENDOCRINE PANCREAS

686 Pancreatic Neuroendocrine Tumor Protocol

Vania Nosé, MD, PhD

SECTION 6: ENDOCRINE SKIN

690 Merkel Cell Carcinoma

Lori A. Erickson, MD

SECTION 7: INHERITED TUMOR

SYNDROMES

700 Familial Isolated Hyperparathyroidism

Vania Nosé, MD, PhD and Lori A. Erickson, MD

704 Glucagon Cell Hyperplasia and Neoplasia

Vania Nosé, MD, PhD

708 Hereditary Pancreatic Cancer Syndrome

Daniel C. Chung, MD and Vania Nosé, MD, PhD

712 Hyperparathyroidism-Jaw Tumor Syndrome

Vania Nosé, MD, PhD and Lori A. Erickson, MD

720 Multiple Endocrine Neoplasia Type 1 (MEN1)

Vania Nosé, MD, PhD and Michelle Menon Miyake, MD

728 Multiple Endocrine Neoplasia Type 2 (MEN2)

Vania Nosé, MD, PhD and Adam Fisch, MD, PhD

736 DICER1 Syndrome

Vania Nosé, MD, PhD and Michelle Menon Miyake, MD

746 Multiple Endocrine Neoplasia Type 4 (MEN4)

Vania Nosé, MD, PhD and Michelle Menon Miyake, MD

752 PTEN-Hamartoma Tumor Syndromes

Vania Nosé, MD, PhD and Adam Fisch, MD, PhD

760 von Hippel-Lindau Syndrome

Vania Nosé, MD, PhD and Carla Martins Alberti, MD

768 Neurofibromatosis Type 1

Vania Nosé, MD, PhD and Michelle Menon Miyake, MD

776 Carney Complex

Vania Nosé, MD, PhD

784 SDH-Deficient Pheochromocytoma and

Paraganglioma

Vania Nosé, MD, PhD and Arthur S. Tischler, MD

788 Syndromic Familial Nonmedullary Thyroid Carcinoma

Vania Nosé, MD, PhD

800 Nonsyndromic Familial Nonmedullary Thyroid

Carcinoma

Vania Nosé, MD, PhD

812 McCune-Albright Syndrome

Vania Nosé, MD, PhD

818 Beckwith-Wiedemann Syndrome

Vania Nosé, MD, PhD and Patricia Nogueira de Sa, MD

SECTION 8: PARANEOPLASTIC

SYNDROMES

828 Ectopic (Paraneoplastic) Syndromes

Lori A. Erickson, MD

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